Thursday, October 14, 2010

Diagnostics

Image 1

On Tuesday 7 September 2010, Tessa was admitted for thoracic radiographs in the radiology department at the Veterinary Specialist Group. Ventral dorsal and left lateral radiographs were taken (see image 1 and 2). It was recorded that a large mass lesion was associated with the caudal left thoracic wall. It was also noted that it appeared to originate from the 11th rib and is around 12cm in diameter. There was no obvious nodular pathology within the pulmonary lung fields (Warman, 2010).
Image 2

While the patient was admitted for radiographs, some other diagnostic tests were completed. These included, a complete blood count and biochemistry panel which were sent off to Gribbles Laboratory for observation (see results below). A packed cell volume and an in house Vetscan reading were also taken. The packed cell volume result was 48% and the Vetscan results were as follows:

Tuesday 7 September – Vetscan (In house)
Specifics
Reading
Reference Range
ALB
35 g/L
25-44
ALP
44 U/L
20-150
ALT
29 U/L
10-118
AMY
525 U/L
200-1200
TBIL
3 umol/L
2-10
BUN
4.4 mmol/L
2.5-8.9
CA
2.71 mmol/L
2.15-2.95
PHOS
1.25 mmol/L
0.94-2.13
CRE
61 umol/L
27-124
GLU
5.3 mmol/L
3.3-6.1
NA+
151 mmol/L
138-160
K+
4.0 mmol/L
3.7-5.8
TP
64 g/L
54-82
GLOB
29 g/L
23-52

On the Vetscan results, it was stated that the quality control was ok and lipaemia reading was at 1+, however haemolysis and ictarus readings were both 0.

The results for the complete blood count and biochemistry panel are as follows:

Tuesday 7 September – Complete blood count (Gribbles)
Specifics
Reading
Reference Range
RBC
6.53x1012/L
5.5-8.2
HB
149 g/L
120-180
HCT
0.44 L/L
0.37-0.55
MCV
67 FL
60-78
MCH
23 PG
20-25
MCHC
342 g/L
310-360
PLAT
276x109 /L
200-500
WBC
9.8x109 /L
6-15
NEUT
81%

NEUTAB
7.9x109 /L
3.6-11.5
LYMPH
13%

LYMPHAB
1.3x109 /L
1-4.8
MONO
4%

MONOAB
0.4x109 /L
0.2-1.5
EOSIN
2%

EOSINAB
0.2x109 /L
0.1-1.5
WBCRAW
9.78x109 /L
6-17

On the copy of the complete blood count results, it was stated that the red cell, leukocyte and 
platelet morphology all appeared normal.

Tuesday 7 September – Biochemistry Panel (Gribbles)
Specifics
Reading
Range
ALB
35 g/L
25-44
ALP
44 U/L
20-150
ALT
29 U/L
10-118
AMY
525 U/L
200-1200
TBIL
3 umol/L
2-10
BUN
4.4 mmol/L
2.5-8.9
CA
2.71 mmol/L
2.15-2.95
PHOS
1.25mmol/L
0.94-2.13
CRE
61 umol/L
27-124
GLU
5.3 mmol/L
3.3-6.1
NA+
151 mmol/”
138-160
K+
4.0 mmol/L
3.7-5.8
TP
64 g/L
54-82
GLOB
29 g/L
23-52

On the copy of the biochemistry panel results, it was stated that the quality control was ok and lipaemia reading was at 1+, however haemolysis and ictarus readings were both 0.

Image 3
Image 4
Following the surgical procedure, a left lateral radiograph was taken to ensure that the chest drain and chest tube were placed correctly during the surgical procedure (see image 3). The mass was sent away to Gribbles Laboratories on Monday 13 September 2010 to get the histopathology tested. On Thursday 16 September 2010, the results were returned. The gross examination stated that the mass was 110mm in diameter (see image 4 and 5) and was a multinodular firm white-yellow encapsulated mass. It was noted that multiple margins were examined and that all the tissue margins that were submitted were similar and composed or irregular multinodular proliferations of cells with lacunar which are surrounded by a light
Image 5
basophilic matrix. Centrally there were large areas of haemorrhage and necrosis. Therefore, the morphologic diagnosis was defined as a chondrosarcoma with necrosis and haemorrhage. A comment was also made that the neoplastic cells do not extend to the surgical margins of the tissue that was submitted and also that chondrosarcomas are locally invasive and metastasis to the lungs are less common and would only occur over a longer interval of time (Gribbles Laboratories, 2010)

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